Format

Send to

Choose Destination
See comment in PubMed Commons below
Curr Opin Microbiol. 2009 Feb;12(1):53-60. doi: 10.1016/j.mib.2008.12.003. Epub 2009 Jan 23.

Pseudomonas syringae type III secretion system effectors: repertoires in search of functions.

Author information

  • 1Department of Plant Pathology and Plant-Microbe Biology, Cornell University, Ithaca, NY 14850, USA. sc688@cornell.edu

Abstract

The ability of Pseudomonas syringae to grow and cause diseases in plants is dependent on the injection of multiple effector proteins into plant cells via the type III secretion system (T3SS). Genome-enabled bioinformatic/experimental methods have comprehensively identified the repertoires of effectors and related T3SS substrates for P. syringae pv. tomato DC3000 and three other sequenced strains. The effector repertoires are diverse and internally redundant. Insights into effector functions are being gained through the construction of mutants lacking one or more effector genes, which may be reduced in growth in planta, and through gain-of-function assays for the ability of single effectors to suppress plant innate immune defenses, manipulate hormone signaling, elicit cell death, and/or display biochemical activities on plant protein targets.

PMID:
19168384
DOI:
10.1016/j.mib.2008.12.003
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center