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Cell. 2009 Jan 23;136(2):209-10. doi: 10.1016/j.cell.2009.01.005.

p38delta and PKD1: kinase switches for insulin secretion.

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1
Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología, CSIC, Campus de Cantoblanco, UAM, 28049 Madrid, Spain. acuenda@cnb.csic.es

Abstract

Insufficient production of the hormone insulin by pancreatic beta cells results in diabetes. In this issue, Sumara et al. (2009) report key roles for the protein kinases p38delta and PKD1 in the regulation of insulin secretion as well as in the survival of pancreatic beta cells.

PMID:
19167323
DOI:
10.1016/j.cell.2009.01.005
[Indexed for MEDLINE]
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