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Clin Perinatol. 2009 Mar;36(1):177-88. doi: 10.1016/j.clp.2008.09.016.

Postnatal corticosteroids for bronchopulmonary dysplasia.

Author information

1
Division of Pulmonary Biology, Cincinnati Children's Hospital, University of Cincinnati, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA. alan.jobe@cchmc.org

Abstract

Corticosteroids are used to improve lung function in infants who are progressing toward bronchopulmonary dysplasia. Corticosteroids facilitate extubation, but there is conflicting information about adverse effects on the developing brain. An approach to minimizing risk is to use low-dose, short-duration treatments in the highest risk ventilator-dependent patients. Questions remain about which corticosteroid is the safest and how to dose that corticosteroid.

PMID:
19161874
PMCID:
PMC2663397
DOI:
10.1016/j.clp.2008.09.016
[Indexed for MEDLINE]
Free PMC Article

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