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Dev Cell. 2009 Jan;16(1):3-4. doi: 10.1016/j.devcel.2008.12.013.

A Tf-independent iron transport system required for organogenesis.

Author information

1
Department of Pathology, School of Medicine, University of Utah, Salt Lake City, UT 84132, USA.

Abstract

Cells require iron as a cofactor for proteins that are essential for growth. While delivery of iron to cells by transferrin is well known, Li et al. in this issue of Developmental Cell show that ferritin, through its binding to the cell surface Scara5 receptor, can also deliver iron to cells, permitting kidney organogenesis.

PMID:
19154711
DOI:
10.1016/j.devcel.2008.12.013
[Indexed for MEDLINE]
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