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Immunity. 2009 Jan 16;30(1):9-11. doi: 10.1016/j.immuni.2008.12.010.

Interleukin-17A and interleukin-17F: a tale of two cytokines.

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1
Children's Hospital of Pittsburgh, Rangos Research Center, Pittsburgh, PA 15201, USA.

Abstract

In this issue of Immunity, Ishigame et al. (2009) show that interleukin-17A (IL-17A) mediates autoimmunity whereas both IL-17A and IL-17F are required for mucosal immunity. IL-17A may be more pathologic by inducing proinflammatory cytokines.

PMID:
19144313
DOI:
10.1016/j.immuni.2008.12.010
[Indexed for MEDLINE]
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