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Indian J Pathol Microbiol. 2009 Jan-Mar;52(1):69-70.

Anaplastic large-cell lymphoma with florid granulomatous reaction: a case report and review of literature.

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  • 1Department of Pathology, Chettinad Health City, IT highway Padur, Kancheepuram, India.


Granulomatous reactions have been reported in association with lymphomas, more often with Hodgkins disease than with Non-Hodgkins Lymphoma. Not many reports are available on the association of anaplastic large-cell lymphoma with sarcoid-type granuloma. Herein, we report a case of an elderly female with generalized lymphadenopathy who had a florid granulomatous reaction almost masking the lymphoma cells in the lymph node biopsy. A detailed clinical history, careful histological examination and immunohistochemistry helped in attaining the correct diagnosis.

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