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Cancer Genet Cytogenet. 1991 Aug;55(1):79-84.

Cytogenetic evaluation of 20 cultured primary prostatic tumors.

Author information

1
Department of Pediatrics, Eastern Virginia Medical School, Norfolk 23507.

Abstract

We report the cytogenetic evaluation of 20 cultured cell strains derived from primary prostatic adenocarcinomas obtained from radical prostatectomies. The majority of the strains contained cells with only normal male karyotypes (46,XY), but cytogenetically abnormal clonal populations were found in five strains. Two of those strains contained aberrations involving the Y chromosome, one with a -Y and one with a +Y. Three strains (one of which also had the XYY karyotype) exhibited cells with double-minute chromosomes and four strains contained near tetraploid cells.

PMID:
1913611
DOI:
10.1016/0165-4608(91)90238-p
[Indexed for MEDLINE]

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