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BMC Bioinformatics. 2009 Jan 9;10:14. doi: 10.1186/1471-2105-10-14.

MBA: a literature mining system for extracting biomedical abbreviations.

Author information

1
Department of Computer Science and Technology, University of Science and Technology of China Hefei, Anhui, PR China. xuyun@ustc.edu.cn

Abstract

BACKGROUND:

The exploding growth of the biomedical literature presents many challenges for biological researchers. One such challenge is from the use of a great deal of abbreviations. Extracting abbreviations and their definitions accurately is very helpful to biologists and also facilitates biomedical text analysis. Existing approaches fall into four broad categories: rule based, machine learning based, text alignment based and statistically based. State of the art methods either focus exclusively on acronym-type abbreviations, or could not recognize rare abbreviations. We propose a systematic method to extract abbreviations effectively. At first a scoring method is used to classify the abbreviations into acronym-type and non-acronym-type abbreviations, and then their corresponding definitions are identified by two different methods: text alignment algorithm for the former, statistical method for the latter.

RESULTS:

A literature mining system MBA was constructed to extract both acronym-type and non-acronym-type abbreviations. An abbreviation-tagged literature corpus, called Medstract gold standard corpus, was used to evaluate the system. MBA achieved a recall of 88% at the precision of 91% on the Medstract gold-standard EVALUATION Corpus.

CONCLUSION:

We present a new literature mining system MBA for extracting biomedical abbreviations. Our evaluation demonstrates that the MBA system performs better than the others. It can identify the definition of not only acronym-type abbreviations including a little irregular acronym-type abbreviations (e.g., <CNS1, cyclophilin seven suppressor>), but also non-acronym-type abbreviations (e.g., <Fas, CD95>).

PMID:
19134199
PMCID:
PMC2639376
DOI:
10.1186/1471-2105-10-14
[Indexed for MEDLINE]
Free PMC Article

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