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J Am Chem Soc. 2009 Feb 4;131(4):1362-3. doi: 10.1021/ja8077973.

X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.

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1
Department of Chemistry, The University of Chicago, Chicago, Illinois 60637, USA.

Abstract

Racemic protein crystallography, enabled by total chemical synthesis, has allowed us to determine the X-ray structure of native scorpion toxin BmBKTx1; direct methods were used for phase determination. This is the first example of a protein racemate that crystallized in space group I41/a.

PMID:
19133782
PMCID:
PMC2647749
DOI:
10.1021/ja8077973
[Indexed for MEDLINE]
Free PMC Article
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