Format

Send to

Choose Destination
Bioorg Med Chem Lett. 2009 Feb 15;19(4):1206-9. doi: 10.1016/j.bmcl.2008.12.073. Epub 2008 Dec 25.

Discovery of 2-(alpha-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS.

Author information

1
Cytopia Research Pty Ltd, 576 Swan Street, Richmond, VIC. 3121, Australia.

Abstract

A series of 2-(alpha-methylbenzylamino) pyrazines have shown to be potent inhibitors of the FMS tyrosine receptor kinase. Details of SAR studies, modeling and synthesis of compounds within this series are reported.

PMID:
19128971
DOI:
10.1016/j.bmcl.2008.12.073
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center