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Cell Stem Cell. 2009 Jan 9;4(1):9-10. doi: 10.1016/j.stem.2008.12.003.

Exposing hidden dimensions of embryonic stem cell cycle control.

Author information

1
Department of Biochemistry and Molecular Biology, Paul D. Coverdell Center for Biomedical and Health Sciences, The University of Georgia, 500 D.W. Brooks Drive, Athens, GA 30602, USA. sdalton@uga.edu

Abstract

In a recent issue of Nature Genetics, Wang and colleagues (2008) describe a mechanism for how the mir-290 microRNA cluster regulates the cell cycle of murine embryonic stem cells. A focal point of this regulation is the cyclin-dependent kinase inhibitor p21(Cip1).

PMID:
19128789
PMCID:
PMC2712134
DOI:
10.1016/j.stem.2008.12.003
[Indexed for MEDLINE]
Free PMC Article

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