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Clin Exp Immunol. 2009 Feb;155(2):147-55. doi: 10.1111/j.1365-2249.2008.03851.x.

Clinical immunology review series: An approach to the management of pulmonary disease in primary antibody deficiency.

Author information

1
Department of Clinical Immunology, The Royal London Hospital, Whitechapel, UK.

Abstract

The sinopulmonary tract is the major site of infection in patients with primary antibody deficiency syndromes, and structural lung damage arising from repeated sepsis is a major determinant of morbidity and mortality. Patients with common variable immunodeficiency may, in addition, develop inflammatory lung disease, often associated with multi-system granulomatous disease. This review discusses the presentation and management of lung disease in patients with primary antibody deficiency.

PMID:
19128358
PMCID:
PMC2675244
DOI:
10.1111/j.1365-2249.2008.03851.x
[Indexed for MEDLINE]
Free PMC Article

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