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Bull Cancer. 1991;78(7):587-602.

[History and new development of screening and evaluation methods of anticancer drugs used in vivo and in vitro].

[Article in French]

Author information

Rhône-Poulenc-Rorer, centre de recherches de Vitry-Alfortville, unité de cancérologie, Vitry-sur-Seine, France.


Screening methods for the detection of anticancer activity are of crucial importance in order to find solid tumor-specific agents. A review of past screening methods is followed by a description of present methodologies targetted toward the discovery of such agents. Finally, we discuss primary and secondary in vivo evaluation in experimental chemotherapy.

[Indexed for MEDLINE]

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