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J Med Case Rep. 2009 Jan 6;3:4. doi: 10.1186/1752-1947-3-4.

Extramammary Paget's disease of the penis: a case report and review of the literature.

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Regional Cancer Centre, Department of Urology, Wirral University Teaching Hospital, Arrowe Park Road, Upton, Wirral, CH49 5PE, UK.



Extramammary Paget's disease is a rare cutaneous, slow growing, intraepithelial adenocarcinoma developing in the apocrine gland-bearing areas. Isolated Paget's disease of the penis is extremely rare.


We describe the case of an 87-year-old Caucasian male who presented with a non-healing erythematous plaque on the shaft of the penis previously misdiagnosed as Bowen's disease. The diagnosis was made histologically on the excised specimen and was supported by immunohistochemical staining.


Extramammary Paget's disease is a rare disease which can mimic various types of dermatosis. A high index of suspicion is required, combined with biopsy and immunohistochemical staining in order to make the correct diagnosis. Long-term follow-up is mandatory in these patients in order to identify and treat any subsequent recurrence or concurrent malignancy.

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