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Biol Psychiatry. 1991 Jul 15;30(2):190-6.

Fluoxetine-induced suicidality, serotonin, and seasonality.

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1
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425-0742.

Abstract

In spite of the complexities involved in suicide, fluoxetine has been prematurely and simplistically blamed for inducing this phenomenon. A variety of variables must be factored into such an interpretation. Nevertheless, given the complicated psychobiological circumstances involved, acute and rapid changes in serotonin (5-HT) function appear to be important to the understanding of changes in suicidal behavior. Such a mechanism may also explain the robust seasonal peak of suicides in spring.

PMID:
1912109
[Indexed for MEDLINE]
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