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Virology. 2009 Mar 1;385(1):1-4. doi: 10.1016/j.virol.2008.11.045. Epub 2008 Dec 31.

Risks associated with vaccinia virus in the laboratory.

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1
National Center for Zoonotic, Vector-Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. aho3@cdc.gov

Abstract

Vaccinia virus (VACV) is used commonly in research laboratories. Non-highly attenuated strains of VACV are potentially pathogenic in humans, and VACV vaccination and biosafety level 2 facilities and protocols are currently recommended for vaccinated laboratory workers in the United States who handle non-highly attenuated strains of the virus. Despite this, laboratory-related VACV exposures continue to occur and a number of recent instances of VACV infection in non-vaccinated laboratory workers have been documented. We provide a discussion of the usage and risks associated with VACV in laboratory research.

PMID:
19118854
DOI:
10.1016/j.virol.2008.11.045
[Indexed for MEDLINE]
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