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J Am Soc Nephrol. 2009 Jan;20(1):14-22. doi: 10.1681/ASN.2008050493. Epub 2008 Dec 31.

Pregnancy and the kidney.

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1
George Washington University Medical Faculty Associates, 2150 Pennsylvania Avenue NW, Washington, DC 20037, USA. sharonmaynard@gmail.com

Abstract

Nephrologists are frequently called on to diagnose and treat renal disorders in pregnant women. In this review, we update recent literature pertinent to pregnancy and renal disease. We initially begin by describing the application of common clinical estimators of GFR and proteinuria in pregnancy and then summarize recent studies regarding pregnancy in women with chronic kidney disease and the latest information on the use of common renal medications in pregnancy. In the final section, we describe advances in our understanding of the pathophysiology of preeclampsia and the potential clinical implications of these discoveries for screening, prevention, and treatment of preeclampsia.

PMID:
19118150
DOI:
10.1681/ASN.2008050493
[Indexed for MEDLINE]
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