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Arthritis Rheum. 2009 Jan 15;61(1):84-91. doi: 10.1002/art.24370.

Effectiveness of treatment of calcific tendinitis of the shoulder by disodium EDTA.

Author information

1
San Salvatore Hospital of L'Aquila, Via L. Natali 1, 67100 L'Aquila, Italy. angelocacchio@tin.it

Abstract

OBJECTIVE:

To evaluate the effectiveness of disodium EDTA administration in the treatment of calcific tendinitis of the shoulder.

METHODS:

Eighty patients with radiographically verified calcific tendinitis of the shoulder were enrolled between September 2001 and October 2003. Patients were randomly assigned to either a study group (n = 40) or a control group (n = 40). Pain and functional level were evaluated before and after treatment and at 1-year followup. Radiographic modifications in calcifications were evaluated before and after treatment. Disodium EDTA was administered through single needle mesotherapy and 15 minutes of pulsed-mode 1 MHz-ultrasound.

RESULTS:

The study group displayed improvement in all of the parameters analyzed after treatment and at the 1-year followup. Calcifications disappeared completely in 62.5% of the patients in the study group and partially in 22.5%; calcifications partially disappeared in only 15% of the patients in the control group, and none displayed a complete disappearance.

CONCLUSION:

Our results suggest that the use of disodium EDTA for the management of calcific tendinitis of the shoulder is safe and effective, leading to a significant reduction in pain, improvement in shoulder function, and disappearance of calcifications after 4 weeks, without adverse effects.

PMID:
19116968
DOI:
10.1002/art.24370
[Indexed for MEDLINE]
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