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Carbohydr Res. 2009 Mar 10;344(4):507-10. doi: 10.1016/j.carres.2008.12.009. Epub 2008 Dec 16.

Synthesis of water-soluble phthalocyanines bearing four or eight D-galactose units.

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  • 1Departamento de Química, QOPNA, Universidade de Aveiro, Aveiro, Portugal.

Abstract

The synthesis and structural characterization of two glycophthalocyanines with four or eight unprotected D-galactose units is reported. The sugar units are linked to the macrocycle via the hydroxyl group located at C-6. The water solubility promoted by the carbohydrate moieties provides a potential application of these phthalocyanine derivatives as photosensitizers in photodynamic therapy.

PMID:
19114279
DOI:
10.1016/j.carres.2008.12.009
[PubMed - indexed for MEDLINE]
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