Format

Send to

Choose Destination
Phys Rev Lett. 2008 Dec 5;101(23):238101. Epub 2008 Dec 3.

Coordinated chemomechanical cycles: a mechanism for autonomous molecular motion.

Author information

1
University of Oxford, Department of Physics, Parks Road, Oxford OX1 3PU, United Kingdom.

Erratum in

  • Phys Rev Lett. 2009 Apr 3;102(13):139901.

Abstract

The second law of thermodynamics requires that directed motion be accompanied by dissipation of energy. Here we demonstrate the working principles of a bipedal molecular motor. The motor is constructed from DNA and is driven by the hybridization of a DNA fuel. We show how the catalytic activities of the feet can be coordinated to create a Brownian ratchet that is in principle capable of directional and processive movement along a track. This system can be driven away from equilibrium, demonstrating the potential of the motor to do work.

PMID:
19113596
DOI:
10.1103/PhysRevLett.101.238101
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Physical Society
Loading ...
Support Center