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Am J Obstet Gynecol. 2009 May;200(5):e60-2. doi: 10.1016/j.ajog.2008.10.012. Epub 2008 Dec 27.

Investigating the risk of hypertension shortly after pregnancies complicated by preeclampsia.

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  • 1Department of Obstetrics/Gynecology, University of Pennsylvania Health System, Philadelphia, PA, USA.

Abstract

OBJECTIVE:

Women with a history of preeclampsia are at increased risk for long-term cardiovascular morbidity and mortality. This study assessed whether a pregnancy complicated by preeclampsia is associated with an increased prevalence of maternal hypertension and other cardiovascular risk factors shortly after delivery.

STUDY DESIGN:

Seventy-nine cases and 140 controls that had been enrolled in a prospective case-control study were evaluated in this planned follow-up analysis. The presence of hypertension, diabetes and dyslipidemia were assessed by standardized questionnaire 6-13 months after delivery.

RESULTS:

Women with preeclampsia were significantly more likely than controls to have hypertension (adjusted odds ratio, 13.92; 95% CI, 5.17-37.4; P < .001) after adjusting for confounders. Women with preterm preeclampsia also had an increased odds of hypertension (adjusted odds ratio, 18.31; 95% CI, 5.04-66.46; P < .001) compared with controls.

CONCLUSION:

Pregnancy complications, such as preeclampsia, may provide opportunities to identify women at risk for cardiovascular morbidity years before the onset of disease, allowing a window for prevention and intervention.

PMID:
19111719
DOI:
10.1016/j.ajog.2008.10.012
[PubMed - indexed for MEDLINE]
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