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Am J Obstet Gynecol. 2009 Feb;200(2):138.e1-8. doi: 10.1016/j.ajog.2008.10.001. Epub 2008 Dec 25.

Duration of lactation and incidence of myocardial infarction in middle to late adulthood.

Author information

1
Division of Maternal-Fetal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. astuebe@med.unc.edu

Abstract

OBJECTIVE:

We assessed the relation between duration of lactation and maternal incident myocardial infarction.

STUDY DESIGN:

This was a prospective cohort study of 89,326 parous women in the Nurses' Health Study.

RESULTS:

During 1,350,965 person-years of follow-up, 2540 cases of coronary heart disease were diagnosed. Compared with parous women who had never breastfed, women who had breastfed for a lifetime total of 2 years or longer had 37% lower risk of coronary heart disease (95% confidence interval, 23-49%; P for trend < .001), adjusting for age, parity, and stillbirth history. With additional adjustment for early-adult adiposity, parental history, and lifestyle factors, women who had breastfed for a lifetime total of 2 years or longer had a 23% lower risk of coronary heart disease (95% confidence interval, 6-38%; P for trend = .02) than women who had never breastfed.

CONCLUSION:

In a large, prospective cohort, long duration of lactation was associated with a reduced risk of coronary heart disease.

PMID:
19110223
PMCID:
PMC2684022
DOI:
10.1016/j.ajog.2008.10.001
[Indexed for MEDLINE]
Free PMC Article
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