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Cell. 2008 Dec 26;135(7):1172-4. doi: 10.1016/j.cell.2008.12.015.

Here comes the sun: recognition of UV-damaged DNA.

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1
Departments of Medicine and Biochemistry, CCSR1145, Division of Oncology, Stanford University Medical Center, Stanford, CA 94305-5151, USA.

Abstract

The first step in the repair of DNA damage is lesion detection. In this issue, Scrima et al. (2008) report the structure of the complex of DNA Damage-Binding Protein 1 (DDB1) and DDB2 bound to a DNA photodimer, providing critical insight into the repair of DNA damage caused by ultraviolet light.

PMID:
19109889
DOI:
10.1016/j.cell.2008.12.015
[Indexed for MEDLINE]
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