Format

Send to

Choose Destination
Bioorg Med Chem. 2009 Mar 15;17(6):2121-36. doi: 10.1016/j.bmc.2008.11.025. Epub 2008 Nov 18.

A brief tour of myxobacterial secondary metabolism.

Author information

1
Pharmaceutical Biotechnology, Saarland University, PO Box 151150, 66041 Saarbrücken, Germany.

Abstract

Myxobacteria are soil-dwelling, Gram-negative bacteria which are notable not only for their multi-cellular 'social' lifestyles, but for production of structurally diverse secondary metabolites with potential in clinical therapy. Here we briefly review the history of myxobacterial natural products research, provide an overview of their unique secondary metabolism, with an emphasis on assembly line biosynthesis of polyketide and non-ribosomal peptide metabolites, and look to the future of the field.

PMID:
19109025
DOI:
10.1016/j.bmc.2008.11.025
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center