Format

Send to

Choose Destination
See comment in PubMed Commons below
Diabetes Care. 2009 Apr;32(4):683-7. doi: 10.2337/dc08-1638. Epub 2008 Dec 23.

Decline in physical fitness from childhood to adulthood associated with increased obesity and insulin resistance in adults.

Author information

1
Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Melbourne, Australia. terry.dwyer@mcri.edu.au

Abstract

OBJECTIVE:

To examine how fitness in both childhood and adulthood is associated with adult obesity and insulin resistance.

RESEARCH DESIGN AND METHODS:

A prospective cohort study set in Australia in 2004-2006 followed up a cohort of 647 adults who had participated in the Australian Schools Health and Fitness Survey in 1985 and who had undergone anthropometry and cardiorespiratory fitness assessment during the survey. Outcome measures were insulin resistance and obesity, defined as a homeostasis model assessment index above the 75th sex-specific percentile and BMI >or=30 kg/m(2), respectively.

RESULTS:

Lower levels of child cardiorespiratory fitness were associated with increased odds of adult obesity (adjusted odds ratio [OR] per unit decrease 3.0 [95% CI 1.6-5.6]) and insulin resistance (1.7 [1.1-2.6]). A decline in fitness level between childhood and adulthood was associated with increased obesity (4.5 [2.6-7.7]) and insulin resistance (2.1 [1.5-2.9]) per unit decline.

CONCLUSIONS:

A decline in fitness from childhood to adulthood, and by inference a decline in physical activity, is associated with obesity and insulin resistance in adulthood. Programs aimed at maintaining high childhood physical activity levels into adulthood may have potential for reducing the burden of obesity and type 2 diabetes in adults.

PMID:
19106381
PMCID:
PMC2660487
DOI:
10.2337/dc08-1638
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center