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Mol Chem Neuropathol. 1991 Apr;14(2):143-50.

Plasminogen activator inhibitor in acute stroke.

Author information

1
Department of Neurology, University of Essen, Germany.

Abstract

Plasminogen activator inhibitor activity was determined in patients (26 men, 6 women) with acute ischemic stroke (n = 28) and transient ischemic attack (TIA) (n = 4). Age-matched patients (22 men, 10 women) with various nonvascular neurologic diseases served as controls. Plasma levels of plasminogen activator inhibitor activity were significantly higher in the stroke group (p less than 0.003). Serum triglycerides and plasminogen activator inhibitor activity correlated positively in the stroke group (p less than 0.03) and in controls (p less than 0.0001). Our data suggest a possible involvement of plasminogen activator inhibitor activity in the pathophysiology of stroke.

PMID:
1910359
[Indexed for MEDLINE]

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