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Cerebrovasc Dis. 2009;27(2):187-92. doi: 10.1159/000185611. Epub 2008 Dec 18.

Pulse pressure--independent predictor of poor early outcome and mortality following ischemic stroke.

Author information

1
2nd Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, Warsaw, Poland. kgrabska7@wp.pl

Abstract

BACKGROUND:

Pulse pressure (PP) in acute stroke may be related to the outcome. The link between PP in the first week following ischemic stroke and early outcome was assessed.

METHODS:

We calculated mean PPs during the first 7 days after stroke onset in 1,677 patients. Poor outcome at hospital discharge was defined as a modified Rankin scale score of 3 or more points or death. Logistic regression was developed to evaluate PP as an independent predictor of early outcome.

RESULTS:

For patients with poor outcomes the mean PP during the first week was higher than that for patients with non-poor outcomes. A logistic regression model confirmed that elevated mean PP was independently associated with poor outcome at discharge and 30-day mortality.

CONCLUSION:

Elevated PP during the acute phase of ischemic stroke is an independent predictor of poor early outcome at hospital discharge and 30-day mortality.

PMID:
19092241
DOI:
10.1159/000185611
[Indexed for MEDLINE]

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