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Bioorg Khim. 2008 Nov-Dec;34(6):725-33.

[Apoptosis induced by granzyme B].

[Article in Russian]

Author information

1
Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119991 Russia.

Abstract

Results of biochemical studies of apoptosis reactions induced by granzyme B are considered and summarized. Special attention is paid to the reactions of procaspase activation and limited proteolysis of apoptotic targets. Found values of kinetic constants of granzyme B-mediated enzymatic reactions are listed.

PMID:
19088744
[Indexed for MEDLINE]

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