Abstract
Regulation of expression of the gene encoding interleukin 10 by the histone deacetylase HDAC11 emphasizes the ability of an antigen-presenting cell to induce immunity or tolerance in CD4+ T cells.
MeSH terms
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Animals
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Antigen-Presenting Cells / enzymology
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Antigen-Presenting Cells / immunology*
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CD4-Positive T-Lymphocytes / immunology*
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CD4-Positive T-Lymphocytes / metabolism
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Cytokines / biosynthesis
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Gene Expression Regulation*
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Histone Deacetylases / metabolism*
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Humans
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Immune Tolerance*
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Interleukin-10 / genetics*
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Promoter Regions, Genetic / physiology
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Transcription, Genetic
Substances
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Cytokines
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Interleukin-10
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HDAC11 protein, human
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Histone Deacetylases