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Forensic Sci Int Genet. 2008 Sep;2(4):e61-4. doi: 10.1016/j.fsigen.2007.12.009. Epub 2008 Feb 14.

Haplotype diversity in human mitochondrial DNA hypervariable regions I-III in the city of Caracas (Venezuela).

Author information

1
Centro de Biotecnología, Fundación Instituto de Estudios Avanzados (IDEA), Caracas, Venezuela.

Abstract

In order to expand the database of variable DNA for forensic identification purposes in Venezuela, we analyzed the sequence polymorphisms of mitochondrial DNA (mtDNA) hypervariable regions (HVR) I-III from 100 unrelated individuals from the city of Caracas, using PCR amplification and fluorescent-based capillary electrophoresis sequencing method. Dominant haplogroups corresponded to Native Americans followed by African ones. The inclusion of HVR III although useful for sub-haplogroup assignation, added little to the discrimination capacity of our database.

PMID:
19083830
DOI:
10.1016/j.fsigen.2007.12.009
[Indexed for MEDLINE]

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