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Ann Otol Rhinol Laryngol. 1991 Aug;100(8):612-5.

Nasopharyngeal flora in the first three years of life in normal and otitis-prone children.

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Division of Infectious Diseases, State University of New York School of Medicine, Buffalo.


Nasopharyngeal carriage of the three major middle ear pathogens (Streptococcus pneumoniae, nontypeable Hemophilus influenzae, and Moraxella catarrhalis) was evaluated prospectively in a group of 110 children followed up for the first 3 years of life. The findings suggested that nasopharyngeal carriage of middle ear pathogens increases significantly during respiratory illness among the general population of young children; however, otitis-prone children demonstrated a tendency to carry nontypeable H influenzae at an unusually high rate even during health. This propensity to carry nontypeable H influenzae might explain why nontypeable H influenzae is a major cause of recurrent or chronic otitis media.

[Indexed for MEDLINE]

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