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Mol Cell Probes. 1991 Jun;5(3):215-9.

Differentiation of Mycobacterium tuberculosis and Mycobacterium bovis BCG by a polymerase chain reaction assay.

Author information

1
Division of Bacterial Diseases, Centers for Disease Control, Atlanta GA 30333.

Abstract

Mycobacterium tuberculosis and Mycobacterium bovis are closely related species which carry different numbers of the repetitive DNA element IS6110. A polymerase chain reaction assay was developed to assess the copy number of IS6110 in a strain and thereby differentiate these two important human pathogens.

PMID:
1908051
DOI:
10.1016/0890-8508(91)90043-j
[Indexed for MEDLINE]

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