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Neuroscientist. 2009 Jun;15(3):232-42. doi: 10.1177/1073858408326429. Epub 2008 Dec 12.

The predictive brain state: asynchrony in disorders of attention?

Author information

1
Department of Neurological Surgery, Weill Cornell Medical College, New York, NY, USA. jam@ghajar.net

Abstract

It is postulated that a key function of attention in goal-oriented behavior is to reduce performance variability by generating anticipatory neural activity that can be synchronized with expected sensory information. A network encompassing the prefrontal cortex, parietal lobe, and cerebellum may be critical in the maintenance and timing of such predictive neural activity. Dysfunction of this temporal process may constitute a fundamental defect in attention, causing working memory problems, distractibility, and decreased awareness.

PMID:
19074688
PMCID:
PMC4342364
DOI:
10.1177/1073858408326429
[Indexed for MEDLINE]
Free PMC Article

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