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Am J Obstet Gynecol. 2009 Feb;200(2):167.e1-7. doi: 10.1016/j.ajog.2008.08.021. Epub 2008 Dec 13.

Prepregnancy body mass index, gestational weight gain, and risk of hypertensive pregnancy among Latina women.

Author information

1
Division of Biostatistics and Epidemiology, Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003-9304, USA.

Abstract

OBJECTIVE:

Prepregnancy body mass index (BMI) and gestational weight gain have been associated with hypertensive disorders of pregnancy, but previous studies have included few Latinas, a group at increased risk.

STUDY DESIGN:

We examined these associations in the Latina Gestational Diabetes Mellitus Study, a prospective cohort of 1231 women conducted from 2000 to 2004.

RESULTS:

In multivariable analysis, obese women (BMI > 29.0 kg/m(2)) had 2.5 times the risk of hypertensive pregnancy (95% confidence interval [CI], 1.3-4.8) and 2.7 times the risk of preeclampsia (95% CI, 1.2-5.8), compared with women whose BMI was 19.8 to 26.0 kg/m(2). Women with excessive gestational weight gain had a 3-fold increased risk of a hypertensive disorder of pregnancy (95% CI, 1.1-7.2) and a 4-fold risk of preeclampsia (95% CI, 1.2-14.5), compared with women achieving weight gain guidelines.

CONCLUSION:

These findings suggest prepregnancy obesity and excessive weight gain are associated with hypertension in pregnancy in a Latina population and could be potentially modifiable risk factors.

PMID:
19070831
DOI:
10.1016/j.ajog.2008.08.021
[Indexed for MEDLINE]

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