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Diagn Microbiol Infect Dis. 2009 Feb;63(2):233-6. doi: 10.1016/j.diagmicrobio.2008.11.001. Epub 2008 Dec 12.

A global evaluation of voriconazole activity tested against recent clinical isolates of Candida spp.

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Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.


Voriconazole susceptibility testing was performed on 7191 Candida spp. from 78 centers worldwide between 2004 and 2007. Voriconazole was very active in vitro (MIC(50)/MIC(90), 0.008/0.25 microg/mL; 98% susceptible). In comparison to 5866 Candida spp. isolates collected during global surveillance from 1997 to 2001, there were no changes in voriconazole mean MIC or MIC distribution.

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