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Cancer Sci. 2009 Feb;100(2):363-5. doi: 10.1111/j.1349-7006.2008.01025.x.

Transforming growth factor-β signaling and cancer: the 28th Sapporo Cancer Seminar, 25-27 June 2008.

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Department of Molecular Pathology, Graduate School of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, Japan.


The Sapporo Cancer Seminars have been held annually since 1981. The 28th Sapporo Cancer Seminar was held on 26-27 June 2008 at the Hokkaido University Conference Hall, focusing on transforming growth factor (TGF)-β signaling and cancer. More than 150 scientists participated in the seminar, and it provided a great deal of information on the role of TGF-β signaling in carcinogenesis and tumor metastasis. The possible use of TGF-β antagonists for treatment of cancers was also discussed at the seminar.

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