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Br J Dermatol. 2009 Jan;160(1):107-15. doi: 10.1111/j.1365-2133.2008.08953.x. Epub 2008 Nov 25.

Is contact allergy to disperse dyes and related substances associated with textile dermatitis?

Author information

1
Department of Occupational and Environmental Dermatology, Lund University, Malmö University Hospital, Malmö, Sweden. kristina.morgardt-ryberg@med.lu.se

Abstract

BACKGROUND:

Disperse dyes (DDs) are the most common sensitizers among textile dyes, but there is little knowledge of the clinical relevance of positive patch test reactions.

OBJECTIVE:

To investigate if patient-reported textile-related skin problems can be explained by contact allergy to eight different DDs and/or to chemically related substances, by occupation or by atopic constitution, and if the skin problems are influenced by age or sex.

METHODS:

A questionnaire on textile-related skin problems was answered by 858 of 982 consecutively patch tested patients in Malmö, Sweden and in Leuven, Belgium. The baseline series used for patch testing was supplemented with a textile dye mix (TDM) consisting of the eight DDs and with the separate dyes. The association between textile-related skin problems and contact allergy to the DDs and other risk factors was investigated using multiple logistic regression analysis.

RESULTS:

Eighteen per cent of the patients suspected textiles as a cause of their skin problems. Atopic constitution and female sex were risk factors for skin reactions. Synthetic materials were the most common textiles to give skin problems. A significant association was found between self-reported textile-related skin problems and contact allergy to para-phenylenediamine (PPD) [adjusted odds ratio (OR) 2.1; 95% confidence interval (CI) 1.0-4.3]. A similar, but more imprecise, adjusted OR was found for TDM (OR 1.9; 95% CI 0.57-5.6). Contact allergy to black rubber mix was too rare to be evaluated.

CONCLUSIONS:

Contact allergy to PPD was a more prevalent indicator for skin reactions to textiles than the TDM used in this study.

[Indexed for MEDLINE]

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