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Arch Ophthalmol. 2008 Dec;126(12):1626-32. doi: 10.1001/archopht.126.12.1626.

Surgical removal vs observation for idiopathic or ocular histoplasmosis syndrome-associated subfoveal choroidal neovascularization: Vision Preference Value Scale findings from the randomized SST Group H Trial: SST Report No. 17.

Author information

1
Department of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA. ebass@jhmi.edu

Abstract

OBJECTIVE:

To determine whether patients receiving observation vs surgery for subfoveal choroidal neovascularization that was idiopathic or associated with histoplasmosis differed in preference values assigned to their health and vision status.

METHODS:

Before and after enrollment, patients rated their current vision on a scale from 0 (blind) to 100 (perfect vision) and rated blindness and perfect vision on a scale from 0 (dead) to 100 (perfect health and vision). Scores for current vision were converted to a preference value scale (0 represents death; 100, perfect health and vision).

RESULTS:

In 170 patients, no significant difference existed between the observation and surgery arms in median vision preference values at baseline (74 vs 70) or at the 12- (74 vs 78) or 24-month follow-up (77 vs 73) (P > .05). Preference values did not differ between arms for subgroups defined by age, unilateral vs bilateral choroidal neovascularization, or good vs poor baseline visual acuity.

CONCLUSIONS:

Submacular surgery was no better than observation in the preference values patients assigned to their health status, despite previously reported improvements in vision-specific quality of life.

TRIAL REGISTRATION:

(clinicaltrials.gov) Identifier: NCT00000150.

CLINICAL RELEVANCE:

Ophthalmologists should consider the effects on different measures of quality of life when determining treatment for patients similar to those in the Submacular Surgery Trials Group H Trial.

PMID:
19064840
DOI:
10.1001/archopht.126.12.1626
[Indexed for MEDLINE]
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