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Stroke. 2009 Mar;40(3 Suppl):S126-8. doi: 10.1161/STROKEAHA.108.533083. Epub 2008 Dec 8.

Multimodal neuroprotective therapy with induced hypothermia after ischemic stroke.

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  • 1Department of Neuroscience, University of California, San Diego, 200 West Arbor Drive, MC 8466, OPC 3rd Floor, Suite 3, San Diego, CA 92103-8466, USA.


Neuroprotective therapies have so far failed to provide improved neurological function and outcome after stroke. A recent focus on multimodal therapies, including the combination of neuroprotective medications with hypothermia, opens a promising new treatment strategy. Advances in hypothermia administration make it one of the most promising neuroprotective therapies available and an ideal candidate for combination with other neuroprotective approaches.

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