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Bioorg Med Chem Lett. 2009 Jan 15;19(2):524-7. doi: 10.1016/j.bmcl.2008.11.021. Epub 2008 Nov 13.

Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.

Author information

1
Prolysis Ltd, Begbroke Science Park, Sandy Lane, Yarnton, Oxfordshire OX5 1PF, UK.

Abstract

3-Methoxybenzamide is a weak inhibitor of the essential bacterial cell division protein FtsZ. Exploration of the structure-activity relationships of 3-methoxybenzamide analogues led to the identification of potent anti-staphylococcal compounds.

PMID:
19064318
DOI:
10.1016/j.bmcl.2008.11.021
[Indexed for MEDLINE]

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