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J Pediatr Adolesc Gynecol. 2008 Dec;21(6):305-10. doi: 10.1016/j.jpag.2007.09.006.

Complete androgen insensitivity syndrome--a review.

Author information

1
Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, Michigan 48109-0276, USA.

Abstract

This review paper highlights important diagnostic and therapeutic concerns for girls with Complete Androgen Insensitivity Syndrome (CAIS). CAIS is an androgen receptor defect disorder associated with vaginal and uterine agenesis in women with a 46,XY karyotype. The major clinical issues surrounding this syndrome include timing of gonadectomy, hormone replacement, vaginal dilation, and attention to psychological issues.

PMID:
19064222
DOI:
10.1016/j.jpag.2007.09.006
[Indexed for MEDLINE]

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