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J Med Case Rep. 2008 Dec 5;2:373. doi: 10.1186/1752-1947-2-373.

First isolation of two colistin-resistant emerging pathogens, Brevundimonas diminuta and Ochrobactrum anthropi, in a woman with cystic fibrosis: a case report.

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1
Faculté de Médecine et de Pharmacie, Bd Jean Moulin, France. magalie.menuet@wanadoo.fr

Abstract

INTRODUCTION:

Cystic fibrosis afflicted lungs support the growth of many bacteria rarely implicated in other cases of human infections.

CASE PRESENTATION:

We report the isolation and identification, by 16S rRNA amplification and sequencing, of two emerging pathogens resistant to colistin, Brevundimonas diminuta and Ochrobactrum anthropi, in a 17-year-old woman with cystic fibrosis and pneumonia. The patient eventually responded well to a 2-week regime of imipenem and tobramycin.

CONCLUSION:

Our results clearly re-emphasize the emergence of new colistin-resistant pathogens in patients with cystic fibrosis.

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