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Biosci Biotechnol Biochem. 2008 Dec;72(12):3301-5. Epub 2008 Dec 7.

Accumulation of the bioactive peptides, novokinin, LPYPR and rubiscolin, in seeds of genetically modified soybean.

Author information

1
National Agricultural Research Center for Hokkaido Region, Sapporo, Hokkaido, Japan.

Abstract

Novokinin (RPLKPW), LPYPR, and rubiscolin (YPLDLF) are bioactive peptides with respective hypotensive, hypocholesterolemic, and memory-enhancing activities. We generated transgenic soybean lines that expressed modified forms of the alpha' subunit of seed storage protein beta-conglycinin containing tandem repeats of these bioactive peptides. The modified alpha' subunits constituted up to 0.2% of extracted proteins from the transgenic seeds.

PMID:
19060385
DOI:
10.1271/bbb.80468
[Indexed for MEDLINE]
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