Send to

Choose Destination
Anaesthesist. 2008 Dec;57(12):1219-31. doi: 10.1007/s00101-008-1466-z.

[Therapy of head trauma].

[Article in German]

Author information

Klinik für Anästhesiologie, Johannes Gutenberg-Universität Mainz, Mainz, Germany.


The main target of treatment in patients with head trauma is to maintain the physiological parameters within the following normal limits: intracranial pressure (ICP) below 20 mmHg, cerebral perfusion pressure (CPP) between 50 and 70 mmHg, normoxemia (SpO(2) >90%), normocapnia (paCO(2): 35-38 mmHg), normoglycemia (80-130 mg/dl) and normothermia (36.0-37.5 degrees C). Space-occupying intracranial bleeding or edemas must be evacuated immediately. If these interventions do not result in adequate control of ICP and CPP, the next step would be to administer mannitol and barbiturates. Mild hyperventilation, therapeutic hypothermia, or decompressive craniectomy should be used solely in patients with a persistent ICP increase. Infusion of calcium antagonists or glucocorticoids is never indicated in patients with head trauma.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center