Send to

Choose Destination
Curr Opin Plant Biol. 2009 Feb;12(1):29-35. doi: 10.1016/j.pbi.2008.10.006. Epub 2008 Nov 29.

Stomatal development: new signals and fate determinants.

Author information

Department of Biology, University of Central Florida, Orlando, FL 32816-2368, USA.


Stomata and pavement cells are produced by a series of asymmetric divisions and progressive fate transitions within a stem cell lineage. In Arabidopsis, this process is regulated so that new lineages can be inserted between previously differentiated cells while maintaining stomatal spacing. The small peptide EPIDERMAL PATTERNING FACTOR 1 may be a positional signal secreted by stomatal precursors to modulate behavior of nearby cells. Signal-receiving cells may use TOO MANY MOUTHS and ERECTA family receptors and a MAPK pathway to regulate initiation of new lineages, promote asymmetric division, and control the plane of spacing divisions. Cell fate transitions are controlled by basic helix-loop-helix transcription factor (bHLH), MYB, and MADS-box transcription factors, and there is evidence of miRNA regulation. These results provide insight into positive and negative influences on stomatal cell transitions and suggest points of potential environmental regulation.

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center