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Trends Plant Sci. 2009 Jan;14(1):13-20. doi: 10.1016/j.tplants.2008.10.003. Epub 2008 Nov 29.

Revaluating the evolution of the Toc and Tic protein translocons.

Author information

1
University of Iowa, Department of Biology and the Roy J. Carver Center for Comparative Genomics, 446 Biology Building, Iowa City, IA 52242, USA.

Abstract

The origin of the plastid from a cyanobacterial endosymbiont necessitated the establishment of specialized molecular machines (translocons) to facilitate the import of nuclear-encoded proteins into the organelle. To improve our understanding of the evolution of the translocons at the outer and inner envelope membrane of chloroplasts (Toc and Tic, respectively), we critically reassess the prevalent notion that their subunits have a function exclusive to protein import. We propose that many translocon components are multifunctional, conserving ancestral pre-endosymbiotic properties that predate their recruitment into the primitive translocon (putatively composed of subunits Toc34, Toc75 and Tic110 and associated chaperones). Multifunctionality seems to be a hallmark of the Tic complex, in which protein import is integrated with a broad array of plastid processes.

PMID:
19042148
DOI:
10.1016/j.tplants.2008.10.003
[Indexed for MEDLINE]

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