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Osteoporos Int. 2009 Aug;20(8):1347-52. doi: 10.1007/s00198-008-0801-1. Epub 2008 Nov 28.

Spine radiographs to improve the identification of women at high risk for fractures.

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1
Department of Endocrinology, VU University Medical Center, 1081 HV Amsterdam, The Netherlands. c.netelen@vumc.nl

Abstract

SUMMARY:

In women older than 60 years with clinical risk factors for osteoporosis but without osteoporosis based on bone mineral density (T-score >or= -2.5), a systematic survey with X-rays of the spine identified previously unknown vertebral deformities in 21% of women.

INTRODUCTION:

This study determines the prevalence of vertebral deformities in elderly women with clinical risk factors for osteoporosis but with BMD values above the threshold for osteoporosis (T-score >or= -2.5).

METHODS:

Bisphosphonate naïve women older than 60 years attending 35 general practices in the Netherlands with >or=2 clinical risk factors for osteoporosis were invited for BMD measurement (DXA). In women with T-score >or= -2.5 at both spine and the hips, lateral radiographs of the thoracic and lumbar spine were performed.

RESULTS:

Of 631 women with a DXA measurement, 187 (30%) had osteoporosis (T-score < -2.5 at the spine or the hip). Of the remaining 444 women with T-score >or= -2.5 at both spine and hip, 387 had additional spine radiographs, of whom 80 (21%) had at least one vertebral deformity.

CONCLUSION:

In elderly women with clinical risk factors for osteoporosis but BMD T-score >or= -2.5, addition of spine radiographs identified vertebral deformities in 21% (95% CI: 17-25). Since these women are at risk of future fractures, antiosteoporotic treatment should be considered.

PMID:
19039511
DOI:
10.1007/s00198-008-0801-1
[Indexed for MEDLINE]
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