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FEMS Microbiol Lett. 1991 Jan 15;61(2-3):175-9.

Pyrimidine catabolism in Pseudomonas aeruginosa.

Author information

1
Department of Chemistry, South Dakota State University, Brookings 57007.

Abstract

Pyrimidine catabolism in Pseudomonas aeruginosa was investigated. It was found that the pyrimidine bases uracil and thymidine as well as their respective reductive catabolic products could be utilized as sole sources of nitrogen. Reductive degradation of the pyrimidine bases was noted. The reductive catabolic pathway enzymes dihydropyrimidine dehydrogenase, dihydropyrimidinase and N-carbamoyl-beta-alanine amidohydrolase were all detected in minimal medium grown cells. Induction of pyrimidine catabolism by uracil was observed in this pseudomonad. Pyrimidine degradation in P. aeruginosa was not subject to catabolite repression.

PMID:
1903745
DOI:
10.1016/0378-1097(91)90547-n
[Indexed for MEDLINE]

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