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J Appl Bacteriol. 1991 Mar;70(3):239-44.

Effect of growth temperature on virulence of strains of Listeria monocytogenes in the mouse: evidence for a dose dependence.

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1
Department of Microbiology, University of Leicester, UK.

Abstract

Growth of Listeria monocytogenes at 4 degrees C significantly increased its virulence for mice by the intravenous route and the effect was dose-dependent. Virulence was apparent only at a dose of about or above 10(4) viable listerias. At slightly lower doses of about 10(3), no such effect was observed. Growth at 4 degrees C did not increase the virulence of the strains for mice by oral-gastric challenge when given at doses of approximately 10(10).

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