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World J Gastroenterol. 2008 Nov 14;14(42):6453-7.

Role of probiotics, prebiotics and synbiotics in chemoprevention for colorectal cancer.

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3rd Surgical Clinic of the University hospital 'ATTIKON', Rimini 1, 12462, Haidari, Greece.


Colorectal cancer is the third most common form of cancer. Current treatments are all associated with a high risk of complications and a low success rate. Recently, synbiotics have been proposed as a new preventive and therapeutic option. There is no direct experimental evidence for cancer suppression in humans as a result of the consumption of pro-, pre- or synbiotics. However, there is a wealth of evidence emerging from laboratory studies. The mechanisms by which pro-, pre- and synbiotics may inhibit colon cancer are now beginning to be understood and will be addressed in the present review.

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